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TitleFunctional Characterization and Structural Basis of an Efficient Di-C-glycosyltransferase fromGlycyrrhiza glabra.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 142, Page 3506-3512, Year 2020
Publish dateOct 24, 2019 (structure data deposition date)
AuthorsZhang, M. / Li, F.D. / Li, K. / Wang, Z.L. / Wang, Y.X. / He, J.B. / Su, H.F. / Zhang, Z.Y. / Chi, C.B. / Shi, X.M. ...Zhang, M. / Li, F.D. / Li, K. / Wang, Z.L. / Wang, Y.X. / He, J.B. / Su, H.F. / Zhang, Z.Y. / Chi, C.B. / Shi, X.M. / Yun, C.H. / Liu, Z.M. / Zhang, L.R. / Yang, D.H. / Ma, M. / Qiao, X. / Ye, M.
External linksJ. Am. Chem. Soc. / PubMed:31986016
MethodsX-ray diffraction
Resolution1.8 - 2.894 Å
Structure data

PDB-6l5p:
crystal structure of GgCGT in complex with UDP-Glu
Method: X-RAY DIFFRACTION / Resolution: 2.603 Å

PDB-6l5q:
crystal structure of GgCGT in complex with UDP-Gal
Method: X-RAY DIFFRACTION / Resolution: 2.894 Å

PDB-6l5r:
crystal structure of GgCGT in complex with UDP-Glu
Method: X-RAY DIFFRACTION / Resolution: 2.89 Å

PDB-6l5s:
crystal structure of GgCGT in complex with UDP-Glu
Method: X-RAY DIFFRACTION / Resolution: 1.914 Å

PDB-6l7h:
crystal structure of GgCGT in complex with UDP and Nothofagin
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-UPG:
URIDINE-5'-DIPHOSPHATE-GLUCOSE

ChemComp-HOH:
WATER

ChemComp-GDU:
GALACTOSE-URIDINE-5'-DIPHOSPHATE

ChemComp-UDP:
URIDINE-5'-DIPHOSPHATE / UDP*YM

ChemComp-G50:
3-(4-HYDROXYPHENYL)-1-(2,4,6-TRIHYDROXYPHENYL)PROPAN-1-ONE

ChemComp-GOL:
GLYCEROL

ChemComp-E7F:
1-[3-[(2S,3R,4R,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-2,4,6-tris(oxidanyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one

Source
  • glycyrrhiza glabra (plant)
KeywordsTRANSFERASE / di-C-glycosyltransferase

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