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Structure paper

TitleStructural analysis of the intrinsically disordered splicing factor Spp2 and its binding to the DEAH-box ATPase Prp2.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 117, Page 2948-2956, Year 2020
Publish dateMay 6, 2019 (structure data deposition date)
AuthorsHamann, F. / Schmitt, A. / Favretto, F. / Hofele, R. / Neumann, P. / Xiang, S. / Urlaub, H. / Zweckstetter, M. / Ficner, R.
External linksProc. Natl. Acad. Sci. USA / PubMed:31974312
MethodsX-ray diffraction
Resolution1.85 - 2.6 Å
Structure data

PDB-6rm8:
Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-6rm9:
Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-6rma:
Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-6rmb:
Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-6rmc:
Crystal structure of the DEAH-box ATPase Prp2 in complex with Spp2 and ADP
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-SO4:
SULFATE ION

ChemComp-CL:
Unknown entry

ChemComp-BTB:
2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-IPA:
ISOPROPYL ALCOHOL / alkaloid*YM

Source
  • chaetomium thermophilum var. thermophilum dsm 1495 (fungus)
KeywordsHYDROLASE / Prp2 / DEAH-box ATPase / G-patch / spliceosome

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