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Structure paper

TitleStructural basis of polyethylene glycol recognition by antibody.
Journal, issue, pagesJ. Biomed. Sci., Vol. 27, Page 12-12, Year 2020
Publish dateMar 26, 2019 (structure data deposition date)
AuthorsLee, C.C. / Su, Y.C. / Ko, T.P. / Lin, L.L. / Yang, C.Y. / Chang, S.S. / Roffler, S.R. / Wang, A.H.
External linksJ. Biomed. Sci. / PubMed:31907057
MethodsX-ray diffraction
Resolution1.909 - 2.601 Å
Structure data

PDB-6jp7:
Human antibody 32D6 Fab in complex with PEG
Method: X-RAY DIFFRACTION / Resolution: 1.909 Å

PDB-6ju0:
Mouse antibody 3.3 Fab in complex with PEG
Method: X-RAY DIFFRACTION / Resolution: 2.601 Å

PDB-6jwc:
Mouse antibody 2B5 Fab in complex with PEG
Method: X-RAY DIFFRACTION / Resolution: 2.297 Å

Chemicals

ChemComp-P6G:
HEXAETHYLENE GLYCOL / precipitant*YM

ChemComp-3FX:
(2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid

ChemComp-HOH:
WATER

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-TOE:
2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXYL

ChemComp-PE3:
3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL

ChemComp-PG4:
TETRAETHYLENE GLYCOL / precipitant*YM

ChemComp-SO4:
SULFATE ION

ChemComp-12P:
DODECAETHYLENE GLYCOL / precipitant*YM

ChemComp-O4B:
1,4,7,10,13,16-HEXAOXACYCLOOCTADECANE

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / antibody Fab / influenza hemagglutinin / complex structure / specific binding / VIRAL PROTEIN-IMMUNE SYSTEM complex / IMMUNE SYSTEM

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