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Structure paper

TitleCrystal structures of Trypanosoma brucei hypoxanthine - guanine - xanthine phosphoribosyltransferase in complex with IMP, GMP and XMP.
Journal, issue, pagesFebs J., Vol. 286, Page 4721-4736, Year 2019
Publish dateOct 30, 2018 (structure data deposition date)
AuthorsTeran, D. / Dolezelova, E. / Keough, D.T. / Hockova, D. / Zikova, A. / Guddat, L.W.
External linksFebs J. / PubMed:31287615
MethodsX-ray diffraction
Resolution1.993 - 2.96 Å
Structure data

PDB-6mxb:
Crystal structure of Trypanosoma brucei hypoxanthine-guanine-xanthine phosphoribosyltranferase in complex with XMP
Method: X-RAY DIFFRACTION / Resolution: 2.192 Å

PDB-6mxc:
Crystal structure of Trypanosoma brucei hypoxanthine-guanine-xanthine phosphoribosyltranferase in complex with GMP
Method: X-RAY DIFFRACTION / Resolution: 1.993 Å

PDB-6mxd:
Crystal structure of Trypanosoma brucei hypoxanthine-guanine-xanthine phosphoribosyltranferase in complex with IMP
Method: X-RAY DIFFRACTION / Resolution: 2.96 Å

PDB-6mxg:
Crystal structure of Trypanosoma brucei hypoxanthine-guanine phosphoribosyltranferase in complex with XMP
Method: X-RAY DIFFRACTION / Resolution: 2.392 Å

Chemicals

ChemComp-XMP:
XANTHOSINE-5'-MONOPHOSPHATE

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-5GP:
GUANOSINE-5'-MONOPHOSPHATE

ChemComp-IMP:
INOSINIC ACID

ChemComp-SO4:
SULFATE ION

Source
  • trypanosoma brucei brucei (strain 927/4 gutat10.1) (eukaryote)
  • trypanosoma brucei brucei (eukaryote)
KeywordsTRANSFERASE / 6-oxopurine PRTs / Purine salvage / Trypanosoma brucei

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