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-Structure paper
Title | The Quinazolinone Allosteric Inhibitor of PBP 2a Synergizes with Piperacillin and Tazobactam against Methicillin-Resistant Staphylococcus aureus. |
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Journal, issue, pages | Antimicrob. Agents Chemother., Vol. 63, Year 2019 |
Publish date | Jul 25, 2018 (structure data deposition date) |
Authors | Janardhanan, J. / Bouley, R. / Martinez-Caballero, S. / Peng, Z. / Batuecas-Mordillo, M. / Meisel, J.E. / Ding, D. / Schroeder, V.A. / Wolter, W.R. / Mahasenan, K.V. ...Janardhanan, J. / Bouley, R. / Martinez-Caballero, S. / Peng, Z. / Batuecas-Mordillo, M. / Meisel, J.E. / Ding, D. / Schroeder, V.A. / Wolter, W.R. / Mahasenan, K.V. / Hermoso, J.A. / Mobashery, S. / Chang, M. |
External links | Antimicrob. Agents Chemother. / PubMed:30858202 |
Methods | X-ray diffraction |
Resolution | 2.5 - 2.82 Å |
Structure data | PDB-6h5o: PDB-6q9n: |
Chemicals | ChemComp-JPP: ChemComp-CD: ChemComp-HOH: ChemComp-QLN: ChemComp-CL: ChemComp-MUR: |
Source |
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Keywords | HYDROLASE / Penicillin Binding Protein |