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Keywords
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Author
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IF

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Structure paper

TitleStructural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase.
Journal, issue, pagesNucleic Acids Res., Vol. 47, Page 3208-3222, Year 2019
Publish dateSep 20, 2018 (structure data deposition date)
AuthorsDehghani-Tafti, S. / Levdikov, V. / Antson, A.A. / Bax, B. / Sanders, C.M.
External linksNucleic Acids Res. / PubMed:30698796
MethodsX-ray diffraction
Resolution1.13 - 3.96 Å
Structure data

PDB-6hph:
Crystal structure of human Pif1 helicase in complex with AMP-PNP
Method: X-RAY DIFFRACTION / Resolution: 1.13 Å

PDB-6hpq:
Crystal structure of human Pif1 helicase in complex with AMP-PNP, brominated crystal form.
Method: X-RAY DIFFRACTION / Resolution: 1.43 Å

PDB-6hpt:
Crystal structure of human Pif1 helicase, apoform.
Method: X-RAY DIFFRACTION / Resolution: 1.44 Å

PDB-6hpu:
Crystal structure of human Pif1 helicase in complex with ADP-AlF4
Method: X-RAY DIFFRACTION / Resolution: 3.96 Å

Chemicals

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-BR:
BROMIDE ION

ChemComp-SO4:
SULFATE ION

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-ALF:
TETRAFLUOROALUMINATE ION

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Pif1 / 5'-3' DNA helicase / Duplex Unwinding / Telomere Maintenance / DNA Repair

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