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Structure paper

TitleHuman Enteric alpha-Defensin 5 Promotes Shigella Infection by Enhancing Bacterial Adhesion and Invasion.
Journal, issue, pagesImmunity, Year 2018
Publish dateJul 24, 2015 (structure data deposition date)
AuthorsXu, D. / Liao, C. / Zhang, B. / Tolbert, W.D. / He, W. / Dai, Z. / Zhang, W. / Yuan, W. / Pazgier, M. / Liu, J. ...Xu, D. / Liao, C. / Zhang, B. / Tolbert, W.D. / He, W. / Dai, Z. / Zhang, W. / Yuan, W. / Pazgier, M. / Liu, J. / Yu, J. / Sansonetti, P.J. / Bevins, C.L. / Shao, Y. / Lu, W.
External linksImmunity / PubMed:29858013
MethodsX-ray diffraction
Resolution1.752 - 2.403 Å
Structure data

PDB-5cui:
Crystal structure of Human Defensin-5 R28A mutant.
Method: X-RAY DIFFRACTION / Resolution: 2.403 Å

PDB-5cuj:
Crystal structure of Human Defensin-5 Y27A mutant crystal form 2.
Method: X-RAY DIFFRACTION / Resolution: 2.08 Å

PDB-5cum:
Crystal structure of Human Defensin-5 Y27A mutant crystal form 1.
Method: X-RAY DIFFRACTION / Resolution: 1.752 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-PG0:
2-(2-METHOXYETHOXY)ETHANOL / inhibitor, precipitant*YM

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-CA:
Unknown entry

ChemComp-IPA:
ISOPROPYL ALCOHOL

Source
  • homo sapiens (human)
KeywordsANTIMICROBIAL PROTEIN / PANETH CELLS DEFENSIN / HUMAN ALPHA-DEFENSIN / INTESTINAL DEFENSIN

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