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TitleNuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites.
Journal, issue, pagesCell, Vol. 173, Page 693-705.e22, Year 2018
Publish dateNov 25, 2017 (structure data deposition date)
AuthorsYoshizawa, T. / Ali, R. / Jiou, J. / Fung, H.Y.J. / Burke, K.A. / Kim, S.J. / Lin, Y. / Peeples, W.B. / Saltzberg, D. / Soniat, M. ...Yoshizawa, T. / Ali, R. / Jiou, J. / Fung, H.Y.J. / Burke, K.A. / Kim, S.J. / Lin, Y. / Peeples, W.B. / Saltzberg, D. / Soniat, M. / Baumhardt, J.M. / Oldenbourg, R. / Sali, A. / Fawzi, N.L. / Rosen, M.K. / Chook, Y.M.
External linksCell / PubMed:29677513
MethodsX-ray diffraction
Resolution2.9 - 4.05 Å
Structure data

PDB-5yvg:
Crystal structure of Karyopherin beta2 in complex with FUS(full length)
Method: X-RAY DIFFRACTION / Resolution: 4.05 Å

PDB-5yvh:
Crystal structure of Karyopherin beta2 in complex with FUS(371-526)
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-5yvi:
Crystal structure of Karyopherin beta2 in complex with FUS(456-526)
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Source
  • homo sapiens (human)
KeywordsPROTEIN TRANSPORT/RNA BINDING PROTEIN / Importin family / PROTEIN TRANSPORT / PROTEIN TRANSPORT-RNA BINDING PROTEIN complex / TRANSPORT PROTEIN

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