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Structure paper

TitleHow ligand binds to the type 1 insulin-like growth factor receptor.
Journal, issue, pagesNat Commun, Vol. 9, Page 821-821, Year 2018
Publish dateDec 14, 2016 (structure data deposition date)
AuthorsXu, Y. / Kong, G.K. / Menting, J.G. / Margetts, M.B. / Delaine, C.A. / Jenkin, L.M. / Kiselyov, V.V. / De Meyts, P. / Forbes, B.E. / Lawrence, M.C.
External linksNat Commun / PubMed:29483580
MethodsX-ray diffraction
Resolution3.00001618041 - 3.27104018461 Å
Structure data

PDB-5u8q:
Structure of the ectodomain of the human Type 1 insulin-like growth factor receptor in complex with IGF-I
Method: X-RAY DIFFRACTION / Resolution: 3.27104018461 Å

PDB-5u8r:
Structure of the ectodomain of the human Type 1 insulin-like growth factor receptor
Method: X-RAY DIFFRACTION / Resolution: 3.00001618041 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-MLT:
D-MALATE

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-IMD:
IMIDAZOLE

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsTRANSFERASE / Receptor tyrosine kinase / Type 1 insulin-like growth factor receptor / insulin-like growth-factor I / TRANSFERASE/IMMUNE SYSTEM / Receptor / tyrosine kinase / Type 1 insulin-like / growth factor receptor / TRANSFERASE-IMMUNE SYSTEM complex

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