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TitleNatural Parasite Exposure Induces Protective Human Anti-Malarial Antibodies.
Journal, issue, pagesImmunity, Vol. 47, Page 1197-1209.e10, Year 2017
Publish dateSep 12, 2017 (structure data deposition date)
AuthorsTriller, G. / Scally, S.W. / Costa, G. / Pissarev, M. / Kreschel, C. / Bosch, A. / Marois, E. / Sack, B.K. / Murugan, R. / Salman, A.M. ...Triller, G. / Scally, S.W. / Costa, G. / Pissarev, M. / Kreschel, C. / Bosch, A. / Marois, E. / Sack, B.K. / Murugan, R. / Salman, A.M. / Janse, C.J. / Khan, S.M. / Kappe, S.H.I. / Adegnika, A.A. / Mordmuller, B. / Levashina, E.A. / Julien, J.P. / Wardemann, H.
External linksImmunity / PubMed:29195810
MethodsX-ray diffraction
Resolution1.6 - 3.15 Å
Structure data

PDB-5bk0:
Crystal structure of 663 Fab bound to circumsporozoite protein NANP 5-mer
Method: X-RAY DIFFRACTION / Resolution: 3.15 Å

PDB-5bk3:
Crystal structure of the neutralizing anti-circumsporozoite protein 580 antibody
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-5bk5:
Crystal structure of the anti-circumsporozoite protein 663 germline antibody
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-6azm:
Crystal structure of the 580 germline antibody bound to circumsporozoite protein NANP 5-mer
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-6azx:
Crystal structure of the neutralizing anti-circumsporozoite protein 663 antibody
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • plasmodium falciparum (malaria parasite P. falciparum)
KeywordsIMMUNE SYSTEM / Malaria / Circumsporozoite protein / Fab

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