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Structure paper

TitleA histidine pH sensor regulates activation of the Ras-specific guanine nucleotide exchange factor RasGRP1.
Journal, issue, pagesElife, Vol. 6, Year 2017
Publish dateSep 6, 2017 (structure data deposition date)
AuthorsVercoulen, Y. / Kondo, Y. / Iwig, J.S. / Janssen, A. / White, K.A. / Amini, M. / Barber, D.L. / Kuriyan, J. / Roose, J.P.
External linksElife / PubMed:28952923
MethodsX-ray diffraction
Resolution3.1 - 3.302 Å
Structure data

PDB-6axf:
Structure of RasGRP2 in complex with Rap1B
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-6axg:
Structure of RasGRP4 in complex with HRas
Method: X-RAY DIFFRACTION / Resolution: 3.302 Å

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / SIGNALING PROTEIN

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