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Structure paper

TitleZATT (ZNF451)-mediated resolution of topoisomerase 2 DNA-protein cross-links.
Journal, issue, pagesScience, Vol. 357, Page 1412-1416, Year 2017
Publish dateNov 9, 2016 (structure data deposition date)
AuthorsSchellenberg, M.J. / Lieberman, J.A. / Herrero-Ruiz, A. / Butler, L.R. / Williams, J.G. / Munoz-Cabello, A.M. / Mueller, G.A. / London, R.E. / Cortes-Ledesma, F. / Williams, R.S.
External linksScience / PubMed:28912134
MethodsX-ray diffraction
Resolution2.35 - 2.399 Å
Structure data

PDB-5tvp:
SUMO2 bound to Mouse Tdp2 catalytic domain with a 5'-phosphorylated DNA ternary complex
Method: X-RAY DIFFRACTION / Resolution: 2.399 Å

PDB-5tvq:
Mouse Tdp2 catalytic domain bound to SUMO2
Method: X-RAY DIFFRACTION / Resolution: 2.35 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CA:
Unknown entry

ChemComp-ACT:
ACETATE ION

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
Keywordshydrolase/dna / hydrolase / dna repair / endonuclease/exonuclease/phosphatase (EEP) domain / hydrolase-dna complex

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