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Structure paper

TitleDissection of the molecular circuitry controlling virulence in Francisella tularensis.
Journal, issue, pagesGenes Dev., Vol. 31, Page 1549-1560, Year 2017
Publish dateDec 6, 2016 (structure data deposition date)
AuthorsCuthbert, B.J. / Ross, W. / Rohlfing, A.E. / Dove, S.L. / Gourse, R.L. / Brennan, R.G. / Schumacher, M.A.
External linksGenes Dev. / PubMed:28864445
MethodsX-ray diffraction
Resolution2.65 - 3.3 Å
Structure data

PDB-5u51:
Structure of Francisella tularensis heterodimeric SspA (MglA-SspA) in complex with ppGpp
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-5u56:
Structure of Francisella tularensis heterodimeric SspA (MglA-SspA)
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-6alx:
Structure of F. tularensis MglA-SspA solved in the presence of polyP
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-MG:
Unknown entry

ChemComp-G4P:
GUANOSINE-5',3'-TETRAPHOSPHATE

ChemComp-HOH:
WATER

ChemComp-PRO:
PROLINE

Source
  • francisella tularensis (bacteria)
KeywordsTRANSCRIPTION / Stringent starvation protein A / Macrophage growth locus A / ppGpp / GST-fold / MglA / SspA / Francisella tularensis / bioweapon

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