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Structure paper

TitleER retention is imposed by COPII protein sorting and attenuated by 4-phenylbutyrate.
Journal, issue, pagesElife, Vol. 6, Year 2017
Publish dateApr 30, 2017 (structure data deposition date)
AuthorsMa, W. / Goldberg, E. / Goldberg, J.
External linksElife / PubMed:28594326
MethodsX-ray diffraction
Resolution2.394 - 2.905 Å
Structure data

PDB-5vne:
Crystal structure of Sec23a/Sec24a/Sec22 complexed with Emp24 sorting motif
Method: X-RAY DIFFRACTION / Resolution: 2.698 Å

PDB-5vnf:
Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal VV sorting motif
Method: X-RAY DIFFRACTION / Resolution: 2.407 Å

PDB-5vng:
Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal II sorting motif
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-5vnh:
Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal SV sorting motif
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-5vni:
Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal FA sorting motif
Method: X-RAY DIFFRACTION / Resolution: 2.788 Å

PDB-5vnj:
Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal FF sorting motif (ERGIC-53)
Method: X-RAY DIFFRACTION / Resolution: 2.806 Å

PDB-5vnk:
Crystal structure of Sec23a/Sec24a/Sec22 complexed with a C-terminal LL sorting motif
Method: X-RAY DIFFRACTION / Resolution: 2.55 Å

PDB-5vnl:
Crystal structure of Sec23a/Sec24a/Sec22 complexed with 4-phenylbutyric acid (1mM soaking)
Method: X-RAY DIFFRACTION / Resolution: 2.394 Å

PDB-5vnm:
Crystal structure of Sec23a/Sec24a/Sec22 complexed with 4-phenylbutyric acid (15mM soaking)
Method: X-RAY DIFFRACTION / Resolution: 2.765 Å

PDB-5vnn:
Crystal structure of Sec23a/Sec24a/Sec22 complexed with 4-phenylbutyric acid (50mM soaking)
Method: X-RAY DIFFRACTION / Resolution: 2.501 Å

PDB-5vno:
Crystal structure of Sec23a/Sec24a/Sec22
Method: X-RAY DIFFRACTION / Resolution: 2.905 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CLT:
4-PHENYL-BUTANOIC ACID

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
  • moesziomyces aphidis dsm 70725 (fungus)
KeywordsPROTEIN TRANSPORT / COPII / Trafficking / Emp24 / ER retention / p24 / protein trafficking / protein quality control / ERGIC-53

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