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Structure paper

Title3-2-1: Structural insights from stepwise shrinkage of a three-helix Fc-binding domain to a single helix.
Journal, issue, pagesProtein Eng. Des. Sel., Vol. 30, Page 619-625, Year 2017
Publish dateDec 6, 2016 (structure data deposition date)
AuthorsUltsch, M. / Braisted, A. / Maun, H.R. / Eigenbrot, C.
External linksProtein Eng. Des. Sel. / PubMed:28475752
MethodsX-ray diffraction
Resolution1.7 - 2.4994 Å
Structure data

PDB-5u4y:
IgG Fc bound to 3 helix of the B-domain from Protein A
Method: X-RAY DIFFRACTION / Resolution: 2.4994 Å

PDB-5u52:
2 helix minimized version of the B-domain from Protein A (Z34C0 bound to IgG1 Fc (monoclinic form)
Method: X-RAY DIFFRACTION / Resolution: 1.942 Å

PDB-5u66:
Modified single helix from the B-domain of protein A bound to IgG1 Fc
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • staphylococcus aureus (bacteria)
KeywordsTRANSCRIPTION / IgG1 / Fc / helix / B-domain / Protein A / IMMUNE SYSTEM / 2 helix bundle / IgG1 fc / immune system/inhibitor / staple peptide / immune system-inhibitor complex

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