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TitleThe Pyruvate and alpha-Ketoglutarate Dehydrogenase Complexes of Pseudomonas aeruginosa Catalyze Pyocyanin and Phenazine-1-carboxylic Acid Reduction via the Subunit Dihydrolipoamide Dehydrogenase.
Journal, issue, pagesJ. Biol. Chem., Vol. 292, Page 5593-5607, Year 2017
Publish dateDec 15, 2016 (structure data deposition date)
AuthorsGlasser, N.R. / Wang, B.X. / Hoy, J.A. / Newman, D.K.
External linksJ. Biol. Chem. / PubMed:28174304
MethodsX-ray diffraction
Resolution1.35 - 1.79 Å
Structure data

PDB-5u8u:
Dihydrolipoamide dehydrogenase (LpdG) from Pseudomonas aeruginosa
Method: X-RAY DIFFRACTION / Resolution: 1.35 Å

PDB-5u8v:
Dihydrolipoamide dehydrogenase (LpdG) from Pseudomonas aeruginosa bound to NAD+
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

PDB-5u8w:
Dihydrolipoamide dehydrogenase (LpdG) from Pseudomonas aeruginosa bound to NADH
Method: X-RAY DIFFRACTION / Resolution: 1.79 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-DMS:
DIMETHYL SULFOXIDE / DMSO, precipitant*YM

ChemComp-HOH:
WATER

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

ChemComp-NAI:
1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE

Source
  • pseudomonas aeruginosa (strain ucbpp-pa14) (bacteria)
KeywordsOXIDOREDUCTASE / dihydrolipoamide dehydrogenase / NAD(H) binding

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