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TitleTalaromyces marneffei Mp1p Is a Virulence Factor that Binds and Sequesters a Key Proinflammatory Lipid to Dampen Host Innate Immune Response
Journal, issue, pagesCell Chem Biol, Vol. 24, Page 182-194, Year 2017
Publish dateJul 23, 2015 (structure data deposition date)
AuthorsSze, K.H. / Lam, W.H. / Zhang, H. / Ke, Y.H. / Tse, M.K. / Woo, P.C. / Lau, S.K. / Lau, C.C. / Cai, J.P. / Tung, E.T. ...Sze, K.H. / Lam, W.H. / Zhang, H. / Ke, Y.H. / Tse, M.K. / Woo, P.C. / Lau, S.K. / Lau, C.C. / Cai, J.P. / Tung, E.T. / Lo, R.K. / Xu, S. / Kao, R.Y. / Hao, Q. / Yuen, K.Y.
External linksCell Chem Biol / PubMed:28111099
MethodsX-ray diffraction
Resolution1.45 - 1.5 Å
Structure data

PDB-5csd:
Ligand binding domain 2 of Penicillium marneffei MP1 protein in complex with arachidonic acids
Method: X-RAY DIFFRACTION / Resolution: 1.45 Å

PDB-5fb7:
Ligand binding domain 2 of Penicillium marneffei MP1 protein complexed with multiple arachidonic acids
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-ACD:
ARACHIDONIC ACID

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • talaromyces marneffei pm1 (fungus)
KeywordsLIPID BINDING PROTEIN / arachidonic acid / Ligand binding domain / Ligand binding domain 2 / multiple arachidonic acids

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