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Structure paper

TitleStructure Based Substrate Specificity Analysis of Heparan Sulfate 6-O-Sulfotransferases.
Journal, issue, pagesACS Chem. Biol., Vol. 12, Page 73-82, Year 2017
Publish dateAug 15, 2016 (structure data deposition date)
AuthorsXu, Y. / Moon, A.F. / Xu, S. / Krahn, J.M. / Liu, J. / Pedersen, L.C.
External linksACS Chem. Biol. / PubMed:28103688
MethodsX-ray diffraction
Resolution1.95 - 2.1 Å
Structure data

PDB-5t03:
Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and glucuronic acid containing hexasaccharide substrate
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-5t05:
Crystal structure of heparan sulfate 6-O-sulfotransferase with bound PAP and IdoA2S containing hexasaccharide substrate
Method: X-RAY DIFFRACTION / Resolution: 1.952 Å

PDB-5t0a:
Crystal Structure of Heparan Sulfate 6-O-Sulfotransferase with bound PAP and heptasaccharide substrate
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-A3P:
ADENOSINE-3'-5'-DIPHOSPHATE

ChemComp-NPO:
P-NITROPHENOL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-NA:
Unknown entry

ChemComp-TLA:
L(+)-TARTARIC ACID

ChemComp-HOH:
WATER

Source
  • escherichia coli o157:h7 (bacteria)
  • danio rerio (zebrafish)
KeywordsTRANSFERASE / heparan sulfate / sulfotransferase / complex

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