EMDB/PDB/SASBDBから引用されている文献のデータベース

キーワード
構造解析手法	All X線回折 NMR 電子顕微鏡小角散乱中性子線回折線維回折粉末回折赤外分光 EPR FRET 理論モデルハイブリッド
著者・登録者
ジャーナル
IF	>30 >20 >10 >5 all

タイトル	Structural basis for subtype-specific inhibition of the P2X7 receptor.
ジャーナル・号・ページ	Elife, Vol. 5, Year 2016
掲載日	2016年11月28日 (構造データの登録日)
著者	Karasawa, A. / Kawate, T.
リンク	Elife / PubMed:27935479
手法	X線回折
解像度	3.201 - 3.903 Å
構造データ	PDB-5u1l: Crystal structure of the ATP-gated P2X7 ion channel in the closed, apo state 手法: X-RAY DIFFRACTION / 解像度: 3.4 Å PDB-5u1u: Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A740003 手法: X-RAY DIFFRACTION / 解像度: 3.604 Å PDB-5u1v: Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist A804598 手法: X-RAY DIFFRACTION / 解像度: 3.4 Å PDB-5u1w: Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist AZ10606120 手法: X-RAY DIFFRACTION / 解像度: 3.501 Å PDB-5u1x: Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist JNJ47965567 手法: X-RAY DIFFRACTION / 解像度: 3.201 Å PDB-5u1y: Crystal structure of the ATP-gated P2X7 ion channel bound to allosteric antagonist GW791343 手法: X-RAY DIFFRACTION / 解像度: 3.3 Å PDB-5u2h: Crystal structure of the ATP-gated P2X7 ion channel bound to ATP and allosteric antagonist A804598 手法: X-RAY DIFFRACTION / 解像度: 3.903 Å
化合物	ChemComp-NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose / N-アセチル-β-D-グルコサミン / N-アセチルグルコサミン ChemComp-7S4: N-{(1R)-1-[N''-cyano-N'-(quinolin-5-yl)carbamimidamido]-2,2-dimethylpropyl}-2-(3,4-dimethoxyphenyl)acetamide ChemComp-7S1: N-cyano-N'-[(1R)-1-phenylethyl]-N''-quinolin-5-ylguanidine ChemComp-7RY: N-[2-({2-[(2-hydroxyethyl)amino]ethyl}amino)quinolin-5-yl]-2-[(3s,5s,7s)-tricyclo[3.3.1.1~3,7~]decan-1-yl]acetamide / AZ-10606120 ChemComp-7RV: N-{[4-(4-phenylpiperazin-1-yl)oxan-4-yl]methyl}-2-(phenylsulfanyl)pyridine-3-carboxamide ChemComp-7RS: N~2~-(3,4-difluorophenyl)-N-{2-methyl-5-[(piperazin-1-yl)methyl]phenyl}glycinamide ChemComp-ATP: ADENOSINE-5'-TRIPHOSPHATE / ATP / ATP, エネルギー貯蔵分子*YM / アデノシン三リン酸
由来	ailuropoda melanoleuca (ジャイアントパンダ)
キーワード	MEMBRANE PROTEIN (膜タンパク質) / ATP-gated ion channel / no ligand / closed state / membrane protein: ATP-gated ion channel: allosteric antagonist bound: closed state (生体膜) / membrane protein: ATP-gated ion channel: agonist and allosteric antagonist bound: closed state (生体膜)