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Structure paper

TitleStructural insights into Gemin5-guided selection of pre-snRNAs for snRNP assembly
Journal, issue, pagesGenes Dev., Vol. 30, Page 2376-2390, Year 2016
Publish dateSep 17, 2016 (structure data deposition date)
AuthorsXu, C. / Ishikawa, H. / Izumikawa, K. / Li, L. / He, H. / Nobe, Y. / Yamauchi, Y. / Shahjee, H.M. / Wu, X.-H. / Yu, Y.-T. ...Xu, C. / Ishikawa, H. / Izumikawa, K. / Li, L. / He, H. / Nobe, Y. / Yamauchi, Y. / Shahjee, H.M. / Wu, X.-H. / Yu, Y.-T. / Isobe, T. / Takahashi, N. / Min, J.
External linksGenes Dev. / PubMed:27881600
MethodsX-ray diffraction
Resolution1.65 - 1.95 Å
Structure data

PDB-5gxh:
The structure of the Gemin5 WD40 domain with AAUUUUUG
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

PDB-5gxi:
Structure of the Gemin5 WD40 domain in complex with AAUUUUUGAG
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-5tee:
Crystal structure of Gemin5 WD40 repeats in apo form
Method: X-RAY DIFFRACTION / Resolution: 1.65 Å

PDB-5tef:
Crystal structure of Gemin5 WD40 repeats in complex with m7GpppG
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

PDB-5tha:
Gemin5 WD40 repeats in complex with a guanosyl moiety
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-UNX:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

ChemComp-GTG:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE

ChemComp-GP3:
DIGUANOSINE-5'-TRIPHOSPHATE

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN/RNA / snRNP assembly / snRNA / Structural Genomics / Structural Genomics Consortium / SGC / RNA BINDING PROTEIN-RNA complex / SPLICING / RNA BINDING PROTEIN / WD40 repeat

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