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Structure paper

TitleInfluenza immunization elicits antibodies specific for an egg-adapted vaccine strain.
Journal, issue, pagesNat. Med., Vol. 22, Page 1465-1469, Year 2016
Publish dateFeb 22, 2016 (structure data deposition date)
AuthorsRaymond, D.D. / Stewart, S.M. / Lee, J. / Ferdman, J. / Bajic, G. / Do, K.T. / Ernandes, M.J. / Suphaphiphat, P. / Settembre, E.C. / Dormitzer, P.R. ...Raymond, D.D. / Stewart, S.M. / Lee, J. / Ferdman, J. / Bajic, G. / Do, K.T. / Ernandes, M.J. / Suphaphiphat, P. / Settembre, E.C. / Dormitzer, P.R. / Del Giudice, G. / Finco, O. / Kang, T.H. / Ippolito, G.C. / Georgiou, G. / Kepler, T.B. / Haynes, B.F. / Moody, M.A. / Liao, H.X. / Schmidt, A.G. / Harrison, S.C.
External linksNat. Med. / PubMed:27820604
MethodsX-ray diffraction
Resolution1.71 - 3.39 Å
Structure data

PDB-5ibl:
Human antibody 6639 in complex with influenza hemagglutinin H1 X-181
Method: X-RAY DIFFRACTION / Resolution: 3.39 Å

PDB-5ibt:
UCA Fab (unbound) from 6515 Lineage
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-5ibu:
6652 Fab (unbound)
Method: X-RAY DIFFRACTION / Resolution: 1.71 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • influenza a virus
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Hemagglutinin / complex / antibody / vaccine / influenza / unbound

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