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TitleStructural basis for nonneutralizing antibody competition at antigenic site II of the respiratory syncytial virus fusion protein.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 113, Page E6849-E6858, Year 2016
Publish dateMar 16, 2016 (structure data deposition date)
AuthorsMousa, J.J. / Sauer, M.F. / Sevy, A.M. / Finn, J.A. / Bates, J.T. / Alvarado, G. / King, H.G. / Loerinc, L.B. / Fong, R.H. / Doranz, B.J. ...Mousa, J.J. / Sauer, M.F. / Sevy, A.M. / Finn, J.A. / Bates, J.T. / Alvarado, G. / King, H.G. / Loerinc, L.B. / Fong, R.H. / Doranz, B.J. / Correia, B.E. / Kalyuzhniy, O. / Wen, X. / Jardetzky, T.S. / Schief, W.R. / Ohi, M.D. / Meiler, J. / Crowe, J.E.
External linksProc. Natl. Acad. Sci. USA / PubMed:27791117
MethodsX-ray diffraction
Resolution2 - 4.077 Å
Structure data

PDB-5itb:
Crystal structure of the anti-RSV F Fab 14N4
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-5j3d:
Crystal structure of human Fab 14N4 in complex with post-fusion RSV F
Method: X-RAY DIFFRACTION / Resolution: 4.077 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • human respiratory syncytial virus a
KeywordsIMMUNE SYSTEM / antibody / virus / complex

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