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-Structure paper
Title | Beyond CDR-grafting: Structure-guided humanization of framework and CDR regions of an anti-myostatin antibody. |
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Journal, issue, pages | Mabs, Vol. 8, Page 1302-1318, Year 2016 |
Publish date | Dec 2, 2015 (structure data deposition date) |
![]() | Apgar, J.R. / Mader, M. / Agostinelli, R. / Benard, S. / Bialek, P. / Johnson, M. / Gao, Y. / Krebs, M. / Owens, J. / Parris, K. ...Apgar, J.R. / Mader, M. / Agostinelli, R. / Benard, S. / Bialek, P. / Johnson, M. / Gao, Y. / Krebs, M. / Owens, J. / Parris, K. / St Andre, M. / Svenson, K. / Morris, C. / Tchistiakova, L. |
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Methods | X-ray diffraction |
Resolution | 1.76 - 2.7 Å |
Structure data | ![]() PDB-5f3b: ![]() PDB-5f3h: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | Signaling Protein/Immune System / myostatin / antibody / complex / Signaling Protein-Immune System complex |