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Structure paper

TitleAccurate design of megadalton-scale two-component icosahedral protein complexes.
Journal, issue, pagesScience, Vol. 353, Page 389-394, Year 2016
Publish dateMar 5, 2016 (structure data deposition date)
AuthorsBale, J.B. / Gonen, S. / Liu, Y. / Sheffler, W. / Ellis, D. / Thomas, C. / Cascio, D. / Yeates, T.O. / Gonen, T. / King, N.P. / Baker, D.
External linksScience / PubMed:27463675
MethodsX-ray diffraction
Resolution3.5 - 5.588 Å
Structure data

PDB-5im4:
Crystal structure of designed two-component self-assembling icosahedral cage I52-32
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

PDB-5im5:
Crystal structure of designed two-component self-assembling icosahedral cage I53-40
Method: X-RAY DIFFRACTION / Resolution: 3.699 Å

PDB-5im6:
Crystal structure of designed two-component self-assembling icosahedral cage I32-28
Method: X-RAY DIFFRACTION / Resolution: 5.588 Å

Source
  • candida albicans p37005 (yeast)
  • caldanaerobacter subterraneus subsp. tengcongensis (strain dsm 15242 / jcm 11007 / nbrc 100824 / mb4) (bacteria)
  • methanocaldococcus jannaschii (strain atcc 43067 / dsm 2661 / jal-1 / jcm 10045 / nbrc 100440) (archaea)
  • vibrionales bacterium (strain swat-3) (bacteria)
  • burkholderia thailandensis e264 (bacteria)
  • deinococcus radiodurans r1 (radioresistant)
KeywordsPROTEIN BINDING / icosahedron / designed protein cage / two-component / computational design / protein engineering / Rosetta / self-assembling / co-assembling / multimerization / symmetry / nanomaterial / nanostructure

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