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TitleImmuno-targeting the multifunctional CD38 using nanobody
Journal, issue, pagesSci Rep, Vol. 6, Page 27055-27055, Year 2016
Publish dateNov 30, 2015 (structure data deposition date)
AuthorsLi, T. / Qi, S. / Unger, M. / Hou, Y.N. / Deng, Q.W. / Liu, J. / Lam, C.M. / Wang, X.W. / Xin, D. / Zhang, P. ...Li, T. / Qi, S. / Unger, M. / Hou, Y.N. / Deng, Q.W. / Liu, J. / Lam, C.M. / Wang, X.W. / Xin, D. / Zhang, P. / Koch-Nolte, F. / Hao, Q. / Zhang, H. / Lee, H.C. / Zhao, Y.J.
External linksSci Rep / PubMed:27251573
MethodsX-ray diffraction
Resolution1.9 - 2.3 Å
Structure data

PDB-5f1k:
human CD38 in complex with nanobody MU1053
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-5f1o:
human CD38 in complex with nanobody MU551
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-5f21:
human CD38 in complex with nanobody MU375
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
  • lama glama (llama)
KeywordsHYDROLASE/IMMUNE SYSTEM / CD38 / ADP-ribosyl cyclase / cyclic ADP-ribose / X-crystallography / Calcium signaling / nanobody / MU1053 / HYDROLASE-IMMUNE SYSTEM complex / MU551 / MU375

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