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TitleStructural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases.
Journal, issue, pagesMol. Cell, Vol. 62, Page 397-408, Year 2016
Publish dateJan 28, 2016 (structure data deposition date)
AuthorsHamill, S. / Lou, H.J. / Turk, B.E. / Boggon, T.J.
External linksMol. Cell / PubMed:27153537
MethodsX-ray diffraction
Resolution2.2 - 3.5 Å
Structure data

PDB-5hvj:
Crystal structure of LIMK1 D460N mutant in complex with AMP-PNP
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-5hvk:
Crystal structure of LIMK1 mutant D460N in complex with full-length cofilin-1
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-HOH:
WATER

ChemComp-MG:
Unknown entry

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / kinase ATP analog actin-remodeling / kinase substrate actin-remodeling

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