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-Structure paper
Title | Structural and Kinetic Characterization of Diazabicyclooctanes as Dual Inhibitors of Both Serine-beta-Lactamases and Penicillin-Binding Proteins. |
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Journal, issue, pages | Acs Chem. Biol., Vol. 11, Page 864-868, Year 2016 |
Publish date | Dec 11, 2015 (structure data deposition date) |
![]() | King, A.M. / King, D.T. / French, S. / Brouillette, E. / Asli, A. / Alexander, J.A. / Vuckovic, M. / Maiti, S.N. / Parr, T.R. / Brown, E.D. ...King, A.M. / King, D.T. / French, S. / Brouillette, E. / Asli, A. / Alexander, J.A. / Vuckovic, M. / Maiti, S.N. / Parr, T.R. / Brown, E.D. / Malouin, F. / Strynadka, N.C. / Wright, G.D. |
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Methods | X-ray diffraction |
Resolution | 1.67 - 3.01 Å |
Structure data | ![]() PDB-5fa7: ![]() PDB-5fao: ![]() PDB-5fap: ![]() PDB-5faq: ![]() PDB-5fas: ![]() PDB-5fat: ![]() PDB-5fgz: |
Chemicals | ![]() ChemComp-5VR: ![]() ChemComp-HOH: ![]() ChemComp-5VW: ![]() ChemComp-602: ![]() ChemComp-CD: ![]() ChemComp-CL: ![]() ChemComp-CO: ![]() ChemComp-M0E: |
Source |
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![]() | HYDROLASE/HYDROLASE INHIBITOR / HYDROLASE-HYDROLASE INHIBITOR complex / Penicillin-binding-protein / inhibitor / complex |