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Structure paper

TitleStructural Basis for Avoidance of Promutagenic DNA Repair by MutY Adenine DNA Glycosylase.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 17096-17105, Year 2015
Publish dateMar 11, 2015 (structure data deposition date)
AuthorsWang, L. / Lee, S.J. / Verdine, G.L.
External linksJ. Biol. Chem. / PubMed:25995449
MethodsX-ray diffraction
Resolution2.21 - 2.59 Å
Structure data

PDB-4yoq:
Crystal Structure of MutY bound to its anti-substrate
Method: X-RAY DIFFRACTION / Resolution: 2.21 Å

PDB-4yph:
Crystal Structure of MutY bound to its anti-substrate with the disulfide cross-linker reduced
Method: X-RAY DIFFRACTION / Resolution: 2.32 Å

PDB-4ypr:
Crystal Structure of D144N MutY bound to its anti-substrate
Method: X-RAY DIFFRACTION / Resolution: 2.59 Å

Chemicals

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-NA:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • geobacillus stearothermophilus (bacteria)
  • synthetic construct (others)
KeywordsHydrolase/DNA / 8-oxoguanine / base-excision repair / anti-substrate / Hydrolase-DNA complex

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