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TitleStructural insights into 5' flap DNA unwinding and incision by the human FAN1 dimer.
Journal, issue, pagesNat Commun, Vol. 5, Page 5726-5726, Year 2014
Publish dateSep 22, 2014 (structure data deposition date)
AuthorsZhao, Q. / Xue, X. / Longerich, S. / Sung, P. / Xiong, Y.
External linksNat Commun / PubMed:25500724
MethodsX-ray diffraction
Resolution2.2 - 4.2 Å
Structure data

PDB-4rea:
A Nuclease DNA complex
Method: X-RAY DIFFRACTION / Resolution: 3.81 Å

PDB-4reb:
Structural Insights into 5' Flap DNA Unwinding and Incision by the Human FAN1 Dimer
Method: X-RAY DIFFRACTION / Resolution: 4.2 Å

PDB-4rec:
A nuclease-DNA complex form 3
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-SM:
SAMARIUM (III) ION

ChemComp-IOD:
IODIDE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsHydrolase/DNA / HJC / TPR / SAP / structural specific nuclease / FANCD2 / nucleus / Hydrolase-DNA complex / structure specific nuclease / FANCID2

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