Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Insights into the binding of PARP inhibitors to the catalytic domain of human tankyrase-2.
Journal, issue, pages	Acta Crystallogr. ,Sect. D, Vol. 70, Page 2740-2753, Year 2014
Publish date	May 22, 2014 (structure data deposition date)
Authors	Qiu, W. / Lam, R. / Voytyuk, O. / Romanov, V. / Gordon, R. / Gebremeskel, S. / Vodsedalek, J. / Thompson, C. / Beletskaya, I. / Battaile, K.P. ...Qiu, W. / Lam, R. / Voytyuk, O. / Romanov, V. / Gordon, R. / Gebremeskel, S. / Vodsedalek, J. / Thompson, C. / Beletskaya, I. / Battaile, K.P. / Pai, E.F. / Rottapel, R. / Chirgadze, N.Y.
External links	Acta Crystallogr. ,Sect. D / PubMed:25286857
Methods	X-ray diffraction
Resolution	1.5 - 2.6 Å
Structure data	PDB-4pml: Crystal Structure of human Tankyrase 2 in complex with 3-amino-benzamide. Method: X-RAY DIFFRACTION / Resolution: 1.87 Å PDB-4pnl: Crystal structure of TNKS-2 in complex with DR2313. Method: X-RAY DIFFRACTION / Resolution: 1.5 Å PDB-4pnm: Crystal Structure of human Tankyrase 2 in complex with Nu1025. Method: X-RAY DIFFRACTION / Resolution: 2.19 Å PDB-4pnn: Crystal Structure of human Tankyrase 2 in complex with 4HQN. Method: X-RAY DIFFRACTION / Resolution: 1.65 Å PDB-4pnq: Crystal Structure of human Tankyrase 2 in complex with 5AIQ. Method: X-RAY DIFFRACTION / Resolution: 1.85 Å PDB-4pnr: Crystal Structure of human Tankyrase 2 in complex with TIQ-A. Method: X-RAY DIFFRACTION / Resolution: 1.71 Å PDB-4pns: Crystal Structure of human Tankyrase 2 in complex with INH2BP. Method: X-RAY DIFFRACTION / Resolution: 1.65 Å PDB-4pnt: Crystal Structure of human Tankyrase 2 in complex with 1,5-IQD. Method: X-RAY DIFFRACTION / Resolution: 1.6 Å PDB-4tju: Crystal Structure of human Tankyrase 2 in complex with 3,4-CPQ-5-C. Method: X-RAY DIFFRACTION / Resolution: 1.57 Å PDB-4tjw: Crystal Structure of human Tankyrase 2 in complex with PJ-34. Method: X-RAY DIFFRACTION / Resolution: 1.7 Å PDB-4tjy: Crystal Structure of human Tankyrase 2 in complex with ABT-888. Method: X-RAY DIFFRACTION / Resolution: 1.9 Å PDB-4tk0: Crystal Structure of human Tankyrase 2 in complex with DPQ. Method: X-RAY DIFFRACTION / Resolution: 1.65 Å PDB-4tk5: Crystal Structure of human Tankyrase 2 in complex with EB47. Method: X-RAY DIFFRACTION / Resolution: 2.02 Å PDB-4tkf: Crystal Structure of human Tankyrase 2 in complex with IWR-1. Method: X-RAY DIFFRACTION / Resolution: 2.6 Å PDB-4tkg: Crystal Structure of human Tankyrase 2 in complex with AZD2281. Method: X-RAY DIFFRACTION / Resolution: 1.95 Å PDB-4tki: Crystal Structure of human Tankyrase 2 in complex with BSI-201. Method: X-RAY DIFFRACTION / Resolution: 2.15 Å
Chemicals	ChemComp-ZN: Unknown entry ChemComp-3AB: 3-aminobenzamide / 3-Aminobenzamide ChemComp-GOL: GLYCEROL / Glycerol ChemComp-EDO: 1,2-ETHANEDIOL / Ethylene glycol ChemComp-DMS: DIMETHYL SULFOXIDE / DMSO, precipitantYM / Dimethyl sulfoxide ChemComp-IPA: ISOPROPYL ALCOHOL / alkaloidYM / Isopropyl alcohol ChemComp-HOH: WATER / Water ChemComp-DRL: 2-methyl-3,5,7,8-tetrahydro-4H-thiopyrano[4,3-d]pyrimidin-4-one ChemComp-NU1: 8-HYDROXY-2-METHYL-3-HYDRO-QUINAZOLIN-4-ONE ChemComp-JPZ: quinazolin-4(1H)-one ChemComp-32X: 5-aminoisoquinolin-1(4H)-one ChemComp-G18: 4H-thieno[2,3-c]isoquinolin-5-one ChemComp-EOH: ETHANOL / Ethanol ChemComp-32Y: 6-amino-5-iodo-2H-chromen-2-one ChemComp-IQD: 5-hydroxyisoquinolin-1(4H)-one ChemComp-CNQ: 3-(4-CHLOROPHENYL)QUINOXALINE-5-CARBOXAMIDE ChemComp-P34: N~2~,N~2~-DIMETHYL-N~1~-(6-OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)GLYCINAMIDE ChemComp-3GN: 2-[(2S)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-7-carboxamide ChemComp-32Z: 5-[4-(piperidin-1-yl)butoxy]-3,4-dihydroisoquinolin-1(2H)-one ChemComp-UHB: 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide ChemComp-33C: 4-[(3aR,4R,7S,7aS)-1,3-dioxooctahydro-2H-4,7-methanoisoindol-2-yl]-N-(quinolin-8-yl)benzamide ChemComp-09L: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one / medication, inhibitorYM / Olaparib ChemComp-33E: 4-iodo-3-nitrobenzamide / inhibitorYM / Iniparib
Source	homo sapiens (human)
Keywords	TRANSFERASE / PARP-inhibitor / PARP / poly(ADP-ribosylation) polymerase (PARP)