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Structure paper

TitleCrystal structure of a 4-thiouridine synthetase-RNA complex reveals specificity of tRNA U8 modification.
Journal, issue, pagesNucleic Acids Res., Vol. 42, Page 6673-6685, Year 2014
Publish dateMay 16, 2013 (structure data deposition date)
AuthorsNeumann, P. / Lakomek, K. / Naumann, P.T. / Erwin, W.M. / Lauhon, C.T. / Ficner, R.
External linksNucleic Acids Res. / PubMed:24705700
MethodsX-ray diffraction
Resolution2.85 - 3.5 Å
Structure data

PDB-4kr6:
Crystal structure of a 4-thiouridine synthetase - RNA complex
Method: X-RAY DIFFRACTION / Resolution: 2.85 Å

PDB-4kr7:
Crystal structure of a 4-thiouridine synthetase - RNA complex with bound ATP
Method: X-RAY DIFFRACTION / Resolution: 3.421 Å

PDB-4kr9:
Crystal structure of a 4-thiouridine synthetase - RNA complex at 3.5 Angstrom resolution
Method: X-RAY DIFFRACTION / Resolution: 3.5 Å

Chemicals

ChemComp-HG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-ATP:
ADENOSINE-5'-TRIPHOSPHATE / ATP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

Source
  • thermotoga maritima (bacteria)
KeywordsTransferase/rna / tRNA modification / thiouridine / sulfurtransferase / adenylation / THUMP domain / PP-loop motif / 4-thiouridine synthesis / Transferase-rna complex

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