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Structure paper

TitleCharacterization of the proline-utilization pathway in Mycobacterium tuberculosis through structural and functional studies.
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 70, Page 968-980, Year 2014
Publish dateDec 12, 2012 (structure data deposition date)
AuthorsLagautriere, T. / Bashiri, G. / Paterson, N.G. / Berney, M. / Cook, G.M. / Baker, E.N.
External linksActa Crystallogr. ,Sect. D / PubMed:24699642
MethodsX-ray diffraction
Resolution1.6 - 2.5 Å
Structure data

PDB-4idm:
Crystal structure of the Delta-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-4ids:
Crystal structure of the Delta-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 2.04 Å

PDB-4ihi:
Crystal structure of the Delta-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis bound with NAD
Method: X-RAY DIFFRACTION / Resolution: 2.25 Å

PDB-4jdc:
Crystal structure of the Delta-pyrroline-5-carboxylate dehydrogenase from Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAD:
NICOTINAMIDE-ADENINE-DINUCLEOTIDE / NAD*YM

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsOXIDOREDUCTASE / pyrroline dehydrogenase / Aldehyde dehydrogenase / pyrroline-5-carboxylate dehydrogeanse / pyrroline-5-carboxylic acid / dehydrogenation / PruA / delta-pyrroline-5-carboxylic dehydrogenase / pyrroline-5-carboxylate dehydrogenase / pyrroline-5-carboxylate / Rossmann fold / pyrroline-5-carboxylate dehtdrogenase / oxydoreduction

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