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Structure paper

TitleStructural insights into recognition of MDC1 by TopBP1 in DNA replication checkpoint control.
Journal, issue, pagesStructure, Vol. 21, Page 1450-1459, Year 2013
Publish dateOct 31, 2011 (structure data deposition date)
AuthorsLeung, C.C. / Sun, L. / Gong, Z. / Burkat, M. / Edwards, R. / Assmus, M. / Chen, J. / Glover, J.N.
External linksStructure / PubMed:23891287
MethodsX-ray diffraction
Resolution1.9 - 2.6 Å
Structure data

PDB-3uen:
Crystal structure of TopBP1 BRCT4/5 domains
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3ueo:
Crystal structure of TopBP1 BRCT4/5 domains in complex with a phospho-peptide
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

Chemicals

ChemComp-SCN:
THIOCYANATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPEPTIDE BINDING PROTEIN / BRCT domain / phospho-peptide binding

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