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TitleStructures of the Class D Carbapenemases OXA-23 and OXA-146: Mechanistic Basis of Activity against Carbapenems, Extended-Spectrum Cephalosporins, and Aztreonam.
Journal, issue, pagesAntimicrob. Agents Chemother., Vol. 57, Page 4848-4855, Year 2013
Publish dateApr 4, 2013 (structure data deposition date)
AuthorsKaitany, K.C. / Klinger, N.V. / June, C.M. / Ramey, M.E. / Bonomo, R.A. / Powers, R.A. / Leonard, D.A.
External linksAntimicrob. Agents Chemother. / PubMed:23877677
MethodsX-ray diffraction
Resolution1.2 - 1.61 Å
Structure data

PDB-4k0w:
X-ray crystal structure of OXA-23 A220 duplication clinical variant
Method: X-RAY DIFFRACTION / Resolution: 1.2 Å

PDB-4k0x:
X-ray Crystal Structure of OXA-23 from Acinetobacter baumannii
Method: X-RAY DIFFRACTION / Resolution: 1.61 Å

Chemicals

ChemComp-CIT:
CITRIC ACID

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-BCT:
BICARBONATE ION / pH buffer*YM

ChemComp-NA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • acinetobacter baumannii (bacteria)
KeywordsHYDROLASE / Carbapenemase / Cephalosporinase

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