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Structure paper

TitleStructure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Journal, issue, pagesCell Rep., Vol. 3, Page 1885-, Year 2013
Publish dateJun 11, 2013 (structure data deposition date)
AuthorsPeng, W.C. / De Lau, W. / Forneris, F. / Granneman, J.C.M. / Huch, M. / Clevers, H. / Gros, P.
External linksCell Rep. / PubMed:23809763
MethodsX-ray diffraction
Resolution2 - 4.3 Å
Structure data

PDB-4bso:
Crystal structure of R-spondin 1 (Fu1Fu2) - Native
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-4bsp:
Crystal structure of R-spondin 1 (Fu1Fu2) - Holmium soak
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4bsr:
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P22121 crystal form
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-4bss:
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P21 crystal form
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-4bst:
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P6122 crystal form
Method: X-RAY DIFFRACTION / Resolution: 4.3 Å

PDB-4bsu:
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in C2 crystal form
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-HO:
HOLMIUM ATOM

ChemComp-SO4:
SULFATE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / ADULT STEM CELL / LEUCINE-RICH REPEAT G-PROTEIN COUPLED RECEPTOR / FURIN DOMAIN / WNT SIGNALING / CONGENITAL ANONYCHIA / LEUCINE-RICH REPEAT / G-PROTEIN COUPLED RECEPTOR / SIGNALLING PROTEIN

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