タイトル | Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design. |
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ジャーナル・号・ページ | Protein Sci., Vol. 22, Page 1071-, Year 2013 |
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掲載日 | 2013年3月13日 (構造データの登録日) |
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著者 | Singh, O. / Shillings, A. / Craggs, P. / Wall, I. / Rowland, P. / Skarzynski, T. / Hobbs, C.I. / Hardwick, P. / Tanner, R. / Blunt, M. ...Singh, O. / Shillings, A. / Craggs, P. / Wall, I. / Rowland, P. / Skarzynski, T. / Hobbs, C.I. / Hardwick, P. / Tanner, R. / Blunt, M. / Witty, D.R. / Smith, K.J. |
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リンク | Protein Sci. / PubMed:23776076 |
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手法 | X線回折 |
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解像度 | 2.11 - 2.8 Å |
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構造データ | PDB-4bf2: Crystal Structures of Ask1-inhibitor Complexes 手法: X-RAY DIFFRACTION / 解像度: 2.11 Å PDB-4bhn: Crystal Structures of Ask1-inhibitor Complexes 手法: X-RAY DIFFRACTION / 解像度: 2.3 Å PDB-4bib: Crystal Structures of Ask1-inhibitor Complexes 手法: X-RAY DIFFRACTION / 解像度: 2.43 Å PDB-4bic: Crystal Structures of Ask1-inhibitor Complexes 手法: X-RAY DIFFRACTION / 解像度: 2.62 Å PDB-4bid: Crystal Structures of Ask1-inhibitor Complexes 手法: X-RAY DIFFRACTION / 解像度: 2.8 Å PDB-4bie: Crystal Structures of Ask1-inhibitor Complexes 手法: X-RAY DIFFRACTION / 解像度: 2.36 Å |
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化合物 | ChemComp-BH9: 4-tert-butyl-N-[6-(1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-2-yl]benzamide
ChemComp-IEO: 3-cyano-4-(piperidin-4-yloxy)-1H-indole-7-carboxamide
ChemComp-IE4: N-(2-aminoethyl)-5-{1H-pyrrolo[2,3-b]pyridin-3-yl}thiophene-2-sulfonamide
ChemComp-IE8: 5-[(1R)-2-amino-1-phenylethoxy]-2-(furan-3-yl)-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}pyridine
ChemComp-IE6: N-(2-aminoethyl)-5-{2-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl}thiophene-2-sulfonamide
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由来 | ![](img/tx_human.gif) homo sapiens (ヒト)
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キーワード | TRANSFERASE (転移酵素) / STRUCTURE BASED DESIGN / STRUCTURE BASED DESGIN |
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