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Structure paper

TitleStructural evaluation of a mimicry-recognizing paratope: plasticity in antigen-antibody interactions manifests in molecular mimicry.
Journal, issue, pagesJ. Immunol., Vol. 191, Page 456-463, Year 2013
Publish dateSep 8, 2012 (structure data deposition date)
AuthorsTapryal, S. / Gaur, V. / Kaur, K.J. / Salunke, D.M.
External linksJ. Immunol. / PubMed:23733869
MethodsX-ray diffraction
Resolution2 - 2.4 Å
Structure data

PDB-4h0g:
Crystal structure of mimicry-recognizing native 2D10 scFv
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-4h0h:
Crystal structure of mimicry-recognizing 2D10 scFv with peptide
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4h0i:
Crystal Structure of Scfv-2D10 in Complex with Methyl Alpha-D-Mannopyranoside
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

ChemComp-MMA:
methyl alpha-D-mannopyranoside

ChemComp-MG:
Unknown entry

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / molecular mimicry / antigen binding / sugar / single chain antibody / antigen recognition

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