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Structure paper

TitleCrystal Structure Analysis of Human Sirt2 and its Adp-Ribose Complex
Journal, issue, pagesJ. Struct. Biol., Vol. 182, Page 136-, Year 2013
Publish dateDec 18, 2012 (structure data deposition date)
AuthorsMoniot, S. / Schutkowski, M. / Steegborn, C.
External linksJ. Struct. Biol. / PubMed:23454361
MethodsX-ray diffraction
Resolution1.63 - 2.27 Å
Structure data

PDB-3zgo:
Re-refined structure of the human Sirt2 apoform
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

PDB-3zgv:
Structure of human SIRT2 in complex with ADP-ribose
Method: X-RAY DIFFRACTION / Resolution: 2.27 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-P6G:
HEXAETHYLENE GLYCOL / precipitant*YM

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-EOH:
ETHANOL

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION

ChemComp-AR6:
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsHYDROLASE / NAD+-DEPENDENT DEACETYLASE / SIRTUIN

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