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Structure paper

TitleStructural and functional analysis of the regulator of G protein signaling 2-g alpha q complex.
Journal, issue, pagesStructure, Vol. 21, Page 438-448, Year 2013
Publish dateApr 9, 2012 (structure data deposition date)
AuthorsNance, M.R. / Kreutz, B. / Tesmer, V.M. / Sterne-Marr, R. / Kozasa, T. / Tesmer, J.J.
External linksStructure / PubMed:23434405
MethodsX-ray diffraction
Resolution2.71 - 7.4 Å
Structure data

PDB-4ekc:
Structure of human regulator of G protein signaling 2 (RGS2) in complex with murine Galpha-q(R183C)
Method: X-RAY DIFFRACTION / Resolution: 7.4 Å

PDB-4ekd:
Structure of human regulator of G protein signaling 2 (RGS2) in complex with murine Galpha-q(R183C)
Method: X-RAY DIFFRACTION / Resolution: 2.71 Å

Chemicals

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM

ChemComp-ALF:
TETRAFLUOROALUMINATE ION

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-CO:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN/INHIBITOR / GTP-binding protein fold / Regulator / G protein signaling / RGS / homology domain / GTPase activation / SIGNALING PROTEIN-INHIBITOR complex / GTP-binding / Regulator of G protein signaling

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