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Structure paper

TitleCrystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 151, Page 1557-1568, Year 2012
Publish dateJun 25, 2012 (structure data deposition date)
AuthorsPos, W. / Sethi, D.K. / Call, M.J. / Schulze, M.S. / Anders, A.K. / Pyrdol, J. / Wucherpfennig, K.W.
External linksCell(Cambridge,Mass. ) / PubMed:23260142
MethodsX-ray diffraction
Resolution2.599 - 3 Å
Structure data

PDB-4fqx:
Crystal structure of HLA-DM bound to HLA-DR1
Method: X-RAY DIFFRACTION / Resolution: 2.599 Å

PDB-4gbx:
Crystal structure of an immune complex at pH 6.5
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsIMMUNE SYSTEM / immune complex / peptide loading / peptide editing / antigen presentation

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