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Structure paper

TitleStructurally Distinct Bacterial TBC-like GAPs Link Arf GTPase to Rab1 Inactivation to Counteract Host Defenses.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 150, Page 1029-1041, Year 2012
Publish dateJun 16, 2012 (structure data deposition date)
AuthorsDong, N. / Zhu, Y. / Lu, Q. / Hu, L. / Zheng, Y. / Shao, F.
External linksCell(Cambridge,Mass. ) / PubMed:22939626
MethodsX-ray diffraction
Resolution2.15 - 4.1 Å
Structure data

PDB-4fma:
EspG structure
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-4fmb:
VirA-Rab1 complex structure
Method: X-RAY DIFFRACTION / Resolution: 3.2 Å

PDB-4fmc:
EspG-Rab1 complex
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-4fmd:
EspG-Rab1 complex structure at 3.05 A
Method: X-RAY DIFFRACTION / Resolution: 3.05 Å

PDB-4fme:
EspG-Rab1-Arf6 complex
Method: X-RAY DIFFRACTION / Resolution: 4.1 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-FMT:
FORMIC ACID / Formic acid

ChemComp-ACY:
ACETIC ACID / Acetic acid

ChemComp-HOH:
WATER / Water

ChemComp-AF3:
ALUMINUM FLUORIDE / Aluminium fluoride

ChemComp-GDP:
GUANOSINE-5'-DIPHOSPHATE / GDP, energy-carrying molecule*YM / Guanosine diphosphate

ChemComp-PGE:
TRIETHYLENE GLYCOL / Polyethylene glycol

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER / Diethylene glycol

ChemComp-GTP:
GUANOSINE-5'-TRIPHOSPHATE / GTP, energy-carrying molecule*YM / Guanosine triphosphate

Source
  • escherichia coli (E. coli)
  • shigella flexneri (bacteria)
  • homo sapiens (human)
KeywordsPROTEIN BINDING / alpha and beta fold / Rab1 GAP / Rab1 GTPase / alpha-beta fold / Rab1-GAP complex / Rab1 / Rab1-GAP / Arf6 effector / Arf6

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