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TitleStructural basis of evasion of cellular adaptive immunity by HIV-1 Nef.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 19, Page 701-706, Year 2012
Publish dateApr 12, 2012 (structure data deposition date)
AuthorsJia, X. / Singh, R. / Homann, S. / Yang, H. / Guatelli, J. / Xiong, Y.
External linksNat. Struct. Mol. Biol. / PubMed:22705789
MethodsX-ray diffraction
Resolution2.58 - 2.9 Å
Structure data

PDB-4emz:
HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second domain)
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

PDB-4en2:
HIV-1 Nef in complex with MHC-I cytoplasmic domain and Mu1 adaptin subunit of AP1 adaptor (second domain)
Method: X-RAY DIFFRACTION / Resolution: 2.58 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus 1
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsVIRAL PROTEIN/IMMUNE SYSTEM / Human immunodeficiency virus 1 / HIV / Nef / MHC-I / antigen presentation / host defense / Adaptor protein complex 1 / Mu1 adaptin subunit / sorting motif recognition / CLASP / membrane trafficking / viral hijacking / VIRAL PROTEIN-IMMUNE SYSTEM complex

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