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TitleEnhancement of alpha-helix mimicry by an alpha / beta-peptide foldamer via incorporation of a dense ionic side-chain array.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 134, Page 7317-7320, Year 2012
Publish dateMar 1, 2012 (structure data deposition date)
AuthorsJohnson, L.M. / Mortenson, D.E. / Yun, H.G. / Horne, W.S. / Ketas, T.J. / Lu, M. / Moore, J.P. / Gellman, S.H.
External linksJ. Am. Chem. Soc. / PubMed:22524614
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-4dzu:
Complex of 3-alpha bound to gp41-5
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-4dzv:
Complex of 4-alpha/beta bound to gp41-5
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
KeywordsDE NOVO PROTEIN / viral fusion / beta amino acid

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