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Structure paper

TitleX-ray structures of LeuT in substrate-free outward-open and apo inward-open states.
Journal, issue, pagesNature, Vol. 481, Page 469-474, Year 2012
Publish dateSep 13, 2011 (structure data deposition date)
AuthorsKrishnamurthy, H. / Gouaux, E.
External linksNature / PubMed:22230955
MethodsX-ray diffraction
Resolution2.994 - 3.22 Å
Structure data

PDB-3tt1:
Crystal Structure of LeuT in the outward-open conformation in complex with Fab
Method: X-RAY DIFFRACTION / Resolution: 3.099 Å

PDB-3tt3:
Crystal Structure of LeuT in the inward-open conformation in complex with Fab
Method: X-RAY DIFFRACTION / Resolution: 3.22 Å

PDB-3tu0:
Crystal structure of T355V, S354A, K288A LeuT mutant in complex with alanine and sodium
Method: X-RAY DIFFRACTION / Resolution: 2.994 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-SOG:
octyl 1-thio-beta-D-glucopyranoside / detergent*YM

ChemComp-HOH:
WATER

ChemComp-ALA:
ALANINE

Source
  • aquifex aeolicus (bacteria)
  • mus musculus (house mouse)
KeywordsTRANSPORT PROTEIN / LeuT fold / transporter / plasma membrane / LeuT-fold / sodium-dependent amino acid transporter

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