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Structure paper

TitleMechanism of mismatch recognition revealed by human MutSbeta bound to unpaired DNA loops
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 19, Page 72-78, Year 2012
Publish dateAug 19, 2011 (structure data deposition date)
AuthorsGupta, S. / Gellert, M. / Yang, W.
External linksNat. Struct. Mol. Biol. / PubMed:22179786
MethodsX-ray diffraction
Resolution2.7 - 4.3 Å
Structure data

PDB-3thw:
Human MutSbeta complexed with an IDL of 4 bases (Loop4) and ADP
Method: X-RAY DIFFRACTION / Resolution: 3.09 Å

PDB-3thx:
Human MutSbeta complexed with an IDL of 3 bases (Loop3) and ADP
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-3thy:
Human MutSbeta complexed with an IDL of 2 bases (Loop2) and ADP
Method: X-RAY DIFFRACTION / Resolution: 2.894 Å

PDB-3thz:
Human MutSbeta complexed with an IDL of 6 bases (Loop6) and ADP
Method: X-RAY DIFFRACTION / Resolution: 4.3 Å

Chemicals

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-HOH:
WATER

ChemComp-NA:
Unknown entry

Source
  • homo sapiens (human)
KeywordsDNA BINDING PROTEIN/DNA / ABC family ATPase / mismatch recognition / mismatched unpaired IDL DNA / DNA BINDING PROTEIN-DNA complex

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