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Structure paper

TitleStructural Basis for the Activation of Innate Immune Pattern Recognition Receptor Rig-I by Viral RNA.
Journal, issue, pagesCell(Cambridge,Mass. ), Vol. 147, Page 423-, Year 2011
Publish dateSep 28, 2011 (structure data deposition date)
AuthorsKowalinski, E. / Lunardi, T. / Mccarthy, A.A. / Louber, J. / Brunel, J. / Grigorov, B. / Gerlier, D. / Cusack, S.
External linksCell(Cambridge,Mass. ) / PubMed:22000019
MethodsX-ray diffraction
Resolution1.44 - 4 Å
Structure data

PDB-4a2p:
Structure of duck RIG-I helicase domain
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-4a2q:
Structure of duck RIG-I tandem CARDs and helicase domain
Method: X-RAY DIFFRACTION / Resolution: 3.4 Å

PDB-4a2v:
Structure of duck RIG-I C-terminal domain (CTD)
Method: X-RAY DIFFRACTION / Resolution: 1.44 Å

PDB-4a2w:
Structure of full-length duck RIG-I
Method: X-RAY DIFFRACTION / Resolution: 3.7 Å

PDB-4a2x:
Structure of duck RIG-I C-terminal domain (CTD) with 14-mer dSRNA
Method: X-RAY DIFFRACTION / Resolution: 4 Å

PDB-4a36:
Structure of duck RIG-I helicase domain bound to 19-mer dsRNA and ATP transition state analogue
Method: X-RAY DIFFRACTION / Resolution: 3.7 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

ChemComp-ADP:
ADENOSINE-5'-DIPHOSPHATE / ADP, energy-carrying molecule*YM

ChemComp-MG:
Unknown entry

ChemComp-AF3:
ALUMINUM FLUORIDE

Source
  • anas platyrhynchos (mallard)
  • synthetic construct (others)
KeywordsHYDROLASE / SUPERFAMILY 2 RNA HELICASE / ATP AND DSRNA BINDING / ANTIVIRAL SIGNALLING PATHWAY / CARD / RNA BINDING PROTEIN/RNA / RNA BINDING PROTEIN-RNA COMPLEX

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