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Structure paper

TitleCrystal structures of the extracellular domain of LRP6 and its complex with DKK1.
Journal, issue, pagesNat. Struct. Mol. Biol., Vol. 18, Page 1204-1210, Year 2011
Publish dateMay 31, 2011 (structure data deposition date)
AuthorsCheng, Z. / Biechele, T. / Wei, Z. / Morrone, S. / Moon, R.T. / Wang, L. / Xu, W.
External linksNat. Struct. Mol. Biol. / PubMed:21984209
MethodsX-ray diffraction
Resolution2.8 - 3.1 Å
Structure data

PDB-3s8v:
Crystal structure of LRP6-Dkk1 complex
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

PDB-3s8z:
Crystal structure of LRP6-E3E4
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-3s94:
Crystal structure of LRP6-E1E2
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
KeywordsSIGNALING PROTEIN / Wnt / receptor / LRP5 / LRP6 / LDL receptor-like protein / Dickkopf (Dkk) / YWTD b-propeller

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