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TitleA Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.
Journal, issue, pagesScience, Vol. 333, Page 850-, Year 2011
Publish dateJul 8, 2011 (structure data deposition date)
AuthorsCorti, D. / Voss, J.E. / Gamblin, S.J. / Codoni, G. / Macagno, A. / Jarrossay, D. / Vachieri, S.G. / Pinna, D. / Minola, A. / Vanzetta, F. ...Corti, D. / Voss, J.E. / Gamblin, S.J. / Codoni, G. / Macagno, A. / Jarrossay, D. / Vachieri, S.G. / Pinna, D. / Minola, A. / Vanzetta, F. / Silacci, C. / Fernandez-Rodriguez, B.M. / Agatic, G. / Bianchi, S. / Giacchetto-Sasselli, I. / Calder, L. / Sallusto, F. / Collins, P.J. / Haire, L.F. / Temperton, N. / Langedijk, J.P.M. / Skehel, J.J. / Lanzavecchia, A.
External linksScience / PubMed:21798894
MethodsX-ray diffraction
Resolution3.001 - 3.41 Å
Structure data

PDB-3ztj:
Structure of influenza A neutralizing antibody selected from cultures of single human plasma cells in complex with human H3 Influenza haemagglutinin.
Method: X-RAY DIFFRACTION / Resolution: 3.41 Å

PDB-3ztn:
STRUCTURE OF INFLUENZA A NEUTRALIZING ANTIBODY SELECTED FROM CULTURES OF SINGLE HUMAN PLASMA CELLS IN COMPLEX WITH HUMAN H1 INFLUENZA HAEMAGGLUTININ.
Method: X-RAY DIFFRACTION / Resolution: 3.001 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
  • influenza a virus
KeywordsIMMUNE SYSTEM/VIRAL PROTEIN / IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX / X31 / MONOCLONAL ANTIBODY / VIRAL PROTEIN/IMMUNE SYSTEM / VIRAL PROTEIN-IMMUNE SYSTEM COMPLEX / MONOCLONAL ANTIBODY.

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