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Structure paper

TitleCrystal Structures of a Family 8 Polysaccharide Lyase Reveal Open and Highly Occluded Substrate-Binding Cleft Conformations.
Journal, issue, pagesProteins, Vol. 79, Page 965-, Year 2011
Publish dateMar 12, 2009 (structure data deposition date)
AuthorsElmabrouk, Z.H. / Vincent, F. / Zhang, M. / Smith, N.L. / Turkenburg, J.P. / Charnock, S.J. / Black, G.W. / Taylor, E.J.
External linksProteins / PubMed:21287626
MethodsX-ray diffraction
Resolution1.94 - 2.3 Å
Structure data

PDB-2wco:
Structures of the Streptomyces coelicolor A3(2) Hyaluronan Lyase in Complex with Oligosaccharide Substrates and an Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 1.94 Å

PDB-2wda:
The X-ray structure of the Streptomyces coelicolor A3 Chondroitin AC Lyase in Complex with Chondroitin sulphate
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-2x03:
The X-ray structure of the Streptomyces coelicolor A3 Chondroitin AC Lyase Y253A mutant
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-GOL:
GLYCEROL

ChemComp-FMT:
FORMIC ACID

ChemComp-HOH:
WATER

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

ChemComp-MG:
Unknown entry

Source
  • streptomyces coelicolor a3(2) (bacteria)
  • streptomyces violaceoruber (bacteria)
  • streptomyces coelicolor (bacteria)
KeywordsLYASE / FAMILY 8 / GLYCOSAMINOGLYCANS (GAGS) HYDROLYSIS / HYALURONATE LYASE / CHONDROITIN LYASE

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