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Structure paper

TitleStructural fine-tuning of a multifunctional cytochrome p450 monooxygenase.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 133, Page 2292-2302, Year 2011
Publish dateOct 5, 2010 (structure data deposition date)
AuthorsZocher, G. / Richter, M.E. / Mueller, U. / Hertweck, C.
External linksJ. Am. Chem. Soc. / PubMed:21280577
MethodsX-ray diffraction
Resolution1.54 - 2.3 Å
Structure data

PDB-3p3l:
Crystal Structure of the Cytochrome P450 monooxygenase AurH (wildtype) from Streptomyces Thioluteus
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3p3o:
Crystal Structure of the Cytochrome P450 Monooxygenase AurH (ntermII) from Streptomyces Thioluteus
Method: X-RAY DIFFRACTION / Resolution: 1.54 Å

PDB-3p3x:
Crystal Structure of the Cytochrome P450 Monooxygenase AurH (nterm-AurH-I) from Streptomyces Thioluteus
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-3p3z:
Crystal Structure of the Cytochrome P450 Monooxygenase AurH from Streptomyces Thioluteus in Complex with Ancymidol
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-HEM:
PROTOPORPHYRIN IX CONTAINING FE

ChemComp-SO4:
SULFATE ION

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

ChemComp-P3Z:
(S)-cyclopropyl(4-methoxyphenyl)pyrimidin-5-ylmethanol

Source
  • streptomyces thioluteus (bacteria)
KeywordsOXIDOREDUCTASE / Cytochrome P450 / Monooxygenase / Cytochrome P450 Monooxygenase / Oxidation of Deoxyaureothin to Aureothin / Oxidation from deoxyaureothin to aureothin

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